csir questions

CSIR Questions !

Todays set of Questions are:
1) ras mutations are inherited to next generation through?
(a) environmental factors
(b) germ line mutations
(c) somatic mutation
(d) spontanous mutation
(e) none

2) Aberrent activation of------- pathway can contribute to the oncogenicity?
(a) anaerobic
(b) mitogenic
(c) carboxylic
(d) aerobic
(e) all

3) Which tumor suppressor gene is most frequently mutated in human cancers?
(a) RB12
(b) TP53
(c) RB84
(d) TP13
(e) ALL

4) Name one prominent factor in the response that arrests the cell
cycle which is activated by P53?
(a) TP53
(b) p21
(c) P-RB
(d) P-APC
(e) RB21

5) p21 is synthesized due to the cell stress by inactivating---------?
(a) DNA repair
(b) cyclins/CDKs complex
(c) protein complex
(d) DNA transcription
(e) all

6) START usually occurs during?
(a) mid-S
(b) mid-G1
(c) end of S
(d) mid-G2
(e) end-G1

7) The most common form of a dominant negative mutant is one that
forms -------- protein containing both mutant and wild type subunits
in p53?
(a) monomeric
(b) homomeric
(c) heteromeric
(d) polymeric
(e) none

8) Tumor T antigens have a variety of function in --------- type of cycle
(a) translation
(b) lytic
(c) lysogenic
(d) translocation
(e) reciprocation

9) The important of the connection between tumorigenesis and loss of
apoptosis is also shown by the properties of the ----- oncogenes?
(a) RB
(b) bcl2
(c) bcl8
(d) p53
(e) all

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An HIV vaccine is the theoretical vaccine which would be given to
persons without HIV in order to vaccinate them against getting HIV,
the virus which causes AIDS. No effective vaccine against HIV exists.
As there is no known cure for AIDS, the search for a vaccine has
become part of medical approaches against the disease.
It has been known for many years that HIV is an extremely difficult
virus to render harmless, and no cure presently exists. Research into
a vaccine is one of several strategies to reduce the worldwide harm
from AIDS, with other approaches based upon antiviral treatments such
as highly active antiretroviral therapy (HAART), and social approaches
such as safe sex.
There is evidence that a vaccine may be possible. Work with monoclonal
antibodies (MAb) has proven that the human body can defend itself
against HIV, and certain individuals remain asymptomatic for decades
after HIV infection. More recently in 2009, a number of potential
candidates for antibodies and early stage results from clinical trials
have been announced by various teams. However these are early results,
and have either not been developed to the point of human testing, or
not fully peer reviewed and replicated by other teams, at this time.

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support4bt@gmail.com
www.sitbiotech.blogspot.com
www.sitbiotech.yolasite.com
9739461028
9037652343