Computational Bioscience - compbio.ucdenver.edu/ - Earn your PhD in Computational Bioscience at UCDenver.

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csir questions

CSIR Questions !

Todays set of Questions are:
1) ras mutations are inherited to next generation through?
(a) environmental factors
(b) germ line mutations
(c) somatic mutation
(d) spontanous mutation
(e) none

2) Aberrent activation of------- pathway can contribute to the oncogenicity?
(a) anaerobic
(b) mitogenic
(c) carboxylic
(d) aerobic
(e) all

3) Which tumor suppressor gene is most frequently mutated in human cancers?
(a) RB12
(b) TP53
(c) RB84
(d) TP13
(e) ALL

4) Name one prominent factor in the response that arrests the cell
cycle which is activated by P53?
(a) TP53
(b) p21
(c) P-RB
(d) P-APC
(e) RB21

5) p21 is synthesized due to the cell stress by inactivating---------?
(a) DNA repair
(b) cyclins/CDKs complex
(c) protein complex
(d) DNA transcription
(e) all

6) START usually occurs during?
(a) mid-S
(b) mid-G1
(c) end of S
(d) mid-G2
(e) end-G1

7) The most common form of a dominant negative mutant is one that
forms -------- protein containing both mutant and wild type subunits
in p53?
(a) monomeric
(b) homomeric
(c) heteromeric
(d) polymeric
(e) none

8) Tumor T antigens have a variety of function in --------- type of cycle
(a) translation
(b) lytic
(c) lysogenic
(d) translocation
(e) reciprocation

9) The important of the connection between tumorigenesis and loss of
apoptosis is also shown by the properties of the ----- oncogenes?
(a) RB
(b) bcl2
(c) bcl8
(d) p53
(e) all

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An HIV vaccine is the theoretical vaccine which would be given to
persons without HIV in order to vaccinate them against getting HIV,
the virus which causes AIDS. No effective vaccine against HIV exists.
As there is no known cure for AIDS, the search for a vaccine has
become part of medical approaches against the disease.
It has been known for many years that HIV is an extremely difficult
virus to render harmless, and no cure presently exists. Research into
a vaccine is one of several strategies to reduce the worldwide harm
from AIDS, with other approaches based upon antiviral treatments such
as highly active antiretroviral therapy (HAART), and social approaches
such as safe sex.
There is evidence that a vaccine may be possible. Work with monoclonal
antibodies (MAb) has proven that the human body can defend itself
against HIV, and certain individuals remain asymptomatic for decades
after HIV infection. More recently in 2009, a number of potential
candidates for antibodies and early stage results from clinical trials
have been announced by various teams. However these are early results,
and have either not been developed to the point of human testing, or
not fully peer reviewed and replicated by other teams, at this time.

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important formulas

1. Molarity M = moles of solute * 1000 / Volume of solution
2. Molality m = moles of solute * 1000/ Mass of solvent in grams
3. Normality N = Gram equivalent weight of Solute * 1000 / Vol of solution
4. Normality = molarity * molecular mass/ equivalent weight
5. Mole fraction x = Moles of solute / (Moles of solute + Moles of Solvent)
6. Mole fraction of solute + Mole fraction of Solvent = 1
   
7. For acids:Normality  = Basicity * Molarity
8. For bases:Normality = Acidity * molarity
9. **Molarity = p * d * 10 / Molar mass (p = mass percentage, d = density of solution). This formula is generally used in laboratories to find the molarity of acids as no molarity is mentioned on the bottles only the purity and density is mention.
10. Normality = p * d * 10 / Equivalent weight
11. m = 1000 * M/ [(1000*d)-(M*gram molecular mass) of solute]
12. **Dilution formula: M1V1 = M2V2 and N1V1 = N2V2
13. **Resulting molarity of a solution is determined by the formula:  M = M1 .V1 + M2 .V2 / (V1 + V2)
14. **x2 = m M1 / (100 + m M1)
    x2 = mole fraction solute, m = molality, M1 = molar mass of solvent)
15. m = 1000 x2 / x1M1   ( x1= mole fraction of solvent)
16. **x2 =M .M1 / [(1000d - M.M2) + M.M1] (M = molarity, M1 = Molar mass of solvent, M2 = Molar mass of solute)
17. M = 100d .x2 / (x1 . M1 +  x2 .M2)

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Used Biotech Instruments - www.cgenetool.com - PCR/RT PCR, DNA seq(ABI3730,3100) Storm860/Typhoon9400. Centrifuge

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phd admission

Ph.D. Admission Secrets - www.HowIGotIntoStanford.com - True Story: How I Got Into the Stanford Psychology PhD Program

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gcp training

Web-based GCP Training - www.clinfosource.com - Enroll now! Convenient, affordable training in GCP clinical research

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VPM CLASSES Biotechnology - www.vpmclasses.com - Best Biotech/Life Sciences COACHING for iit jam, jnu-ceeb,GATE, NET etc

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jobs

Cipla Job Vacancy - HTCareers.in/Pharma_Jobs - Jobs for Experienced Candidates Powered by Shine.com

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Biotechnology Events - www.nature.com/natureevents - Finding biotech conferences & courses has never been easier